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Product Description
AICAR (chemical name: 5-Aminoimidazole-4-carboxamide ribonucleotide) is a peptide, which is an intermediate within the generation of inosine monophosphate and directly related to metabolic regulation.
AICAR shows to be promising in diabetes treatment because of its ability to increase metabolic activity of tissues by changing the composition of muscles in the body.
How does AICAR Work?
AICAR is an adenosine analog that selectively activates AMP-activated protein kinase (AMPK). AMPK regulates lipid and glucose metabolism to maintain cellular energy homeostasis (Hardie and Carling).
A study that was done by the Howard Hughes Medical Center on the effects of AICAR found that mice that were treated with the drug were able to run 44% further even without prior training. AICAR has also been seen to trigger Ketogenesis. Ketogenesis is a biochemical process within the body where broken down fatty acids and amino acids are converted into water soluble molecules called Ketone bodies.
Benefits of AICAR
1 Increase the uptake of glucose in the body
One of the key benefits of AICAR is its effect in increasing the uptake of glucose in the body. Glucose is the source of energy and the increased uptake means that your body is spending more energy than before.
2 Improve metabolic action
Even for people who just want to use the drug as a simple weight loss solution without difficult workout regimens, it can help set the metabolism right so that you can burn more even at rest.
3 A selective supplement targets the skeletal cells and the muscle tissue
AICAR can help people who are extremely obese fine tune their body to a place where they can start an exercise routine. It is a solution that can help you lose weight by doing nothing.
What's the Best AICAR Dosages?
Cutting – For proper cutting using AICAR you'll need a dosage of about 500 milligrams per day for every kilogram of weight. However, if you are stacking with GW501516, you will need only 150 milligrams per day for every kilogram of body weight.
Bulking – The same dosage will also be recommended for bulking. However, in this case it's imperative to stack AICAR with GW501516. 150 milligrams per day with GW501516 should do.
Recomping – You will also need to stack AICAR with GW501516 for recomping. Use 150 milligrams per day and you will be fine.
Method of Stacking
There are a few options you can explore but here are the most common ones:
GW-501516
Andarine
AICAR Potential Side-effects
Despite the strong action AICAR has, it has a number of concerning side effects. To start with, the drug can affect the workings of your heart. It can cause growth of cardiac tissue which may affect the natural blood flow in the body. Some users have also experienced lack of hunger after using the peptide while others in their reviews complained of an extremely dry mouth.
Conclusion
While the product might be out of reach for those who are looking to lose fat, AICAR could be a worthy compound for those who wish to increase endurance and performance. The safety aspects should also be addressed adequately. But there are reasons to believe that things are still at an early stage and we can expect some great news as far as this product is concerned perhaps in the next four to five years. It has properties which are too obvious to ignore.
Product Description
AICAR (chemical name: 5-Aminoimidazole-4-carboxamide ribonucleotide) is a peptide, which is an intermediate within the generation of inosine monophosphate and directly related to metabolic regulation.
AICAR shows to be promising in diabetes treatment because of its ability to increase metabolic activity of tissues by changing the composition of muscles in the body.
How does AICAR Work?
AICAR is an adenosine analog that selectively activates AMP-activated protein kinase (AMPK). AMPK regulates lipid and glucose metabolism to maintain cellular energy homeostasis (Hardie and Carling).
A study that was done by the Howard Hughes Medical Center on the effects of AICAR found that mice that were treated with the drug were able to run 44% further even without prior training. AICAR has also been seen to trigger Ketogenesis. Ketogenesis is a biochemical process within the body where broken down fatty acids and amino acids are converted into water soluble molecules called Ketone bodies.
Benefits of AICAR
1 Increase the uptake of glucose in the body
One of the key benefits of AICAR is its effect in increasing the uptake of glucose in the body. Glucose is the source of energy and the increased uptake means that your body is spending more energy than before.
2 Improve metabolic action
Even for people who just want to use the drug as a simple weight loss solution without difficult workout regimens, it can help set the metabolism right so that you can burn more even at rest.
3 A selective supplement targets the skeletal cells and the muscle tissue
AICAR can help people who are extremely obese fine tune their body to a place where they can start an exercise routine. It is a solution that can help you lose weight by doing nothing.
What's the Best AICAR Dosages?
Cutting – For proper cutting using AICAR you'll need a dosage of about 500 milligrams per day for every kilogram of weight. However, if you are stacking with GW501516, you will need only 150 milligrams per day for every kilogram of body weight.
Bulking – The same dosage will also be recommended for bulking. However, in this case it's imperative to stack AICAR with GW501516. 150 milligrams per day with GW501516 should do.
Recomping – You will also need to stack AICAR with GW501516 for recomping. Use 150 milligrams per day and you will be fine.
Method of Stacking
There are a few options you can explore but here are the most common ones:
GW-501516
Andarine
AICAR Potential Side-effects
Despite the strong action AICAR has, it has a number of concerning side effects. To start with, the drug can affect the workings of your heart. It can cause growth of cardiac tissue which may affect the natural blood flow in the body. Some users have also experienced lack of hunger after using the peptide while others in their reviews complained of an extremely dry mouth.
Conclusion
While the product might be out of reach for those who are looking to lose fat, AICAR could be a worthy compound for those who wish to increase endurance and performance. The safety aspects should also be addressed adequately. But there are reasons to believe that things are still at an early stage and we can expect some great news as far as this product is concerned perhaps in the next four to five years. It has properties which are too obvious to ignore.
